
MS is an individual condition. For some people, MS is characterised
by periods of relapse and remission while for others it has a progressive
pattern. For everyone, it makes life unpredictable. Most people diagnosed
with MS will be described as having relapsing remitting MS, except for the
small number of people who have primary progressive MS.

In relapsing remitting MS, symptoms occur for a period of time
- days, weeks, or months - and then improve, either partially or
completely.
Many people with MS call a relapse an 'attack' because this can
describe the period of time they experience new problems or begin to feel
unwell. A relapse is when new symptoms occur, or old symptoms re-occur, and
last for more than 24 hours.
Relapses happen when inflammatory cells attack nerve fibres in
the brain and spinal cord. if inflammation blocks messages in an area that
has a specific function, such as the optic nerve, then symptoms occur. the
myelin sheath can be damaged and sometimes, the nerve fibre (or axon) itself
is damaged, too.
When the inflammation subsides, symptoms settle down (there may
be some damage left behind which can improve over time) or entirely disappear.
this is known as a remission. Remissions can last any length of time, even
years.
If, after ten to 15 years, your condition hasn't worsened and you
have minimal or no disability, you will be said to have benign MS. This doesn't
mean your MS will be free of problems - it means simply that you haven't
developed major disability, despite having MS for a long time. About 20 per
cent of people with MS have benign MS.

When someone with relapsing remitting MS shows a sustained
deterioration for at least six months - whether or not they have relapses
as well - they are said to have secondary progressive MS. The progression
probably results from the loss of nerve fibres (axons) during past relapses.
Although myelin can repair itself (a process known as remyelination), axons
cannot fully repair themselves.
It isn't always easy for doctors to tell when somebody moves from
relapsing remitting to secondary progressive MS. Some people continue to
have relapses in addition to progressive deterioration, while others don't.
Although nobody's MS starts off being secondary progressive, it's possible
to be told you have this type at diagnosis if you've had unexplained symptoms
for some time.
Not everybody with relapsing remitting MS goes on to develop the
secondary progressive form. On average, buy 15 years, approximately 65 per
cent of people with relapsing remitting MS will have developed secondary
progressive MS.

This is an unusual form of MS, affecting overall perhaps 10 to
15 per cent of people who have MS. People with primary progressive MS tend
to be diagnosed when they are a little older, usually in their forties or
later. Unlike relapsing remitting MS, men are just as likely to be diagnosed
with primary progressive MS as women.
While the other types of MS can affect both the brain and spinal
cord, in primary progressive MS the majority of lesions tend to be found
in the spinal cord. People with primary progressive MS never have any distinct
attacks or remissions but begin with subtle problems that slowly worsen over
time - their MS is progressive from teh beginning.
Problems tend to affect one main area and, for the majority of
people, these are related to walking. However, people with primary progressive
MS can experience any MS symptom.3